Grodno Regional Drama Theatre was established in 1947 on the basis of Bobruisk Regional Drama Theater, which is temporarily housed in Grodno. Theatre, headed by N. Kovyazin, opened its first season premiere of the play by Alexander Ostrovsky's "Truth is well, but happiness is better". The first building, where he worked as a theatrical group was the home of the Grodno elder A. Tizengauzen XVIII century building.

In the postwar years in Belarus have been popular play about the Great Patriotic War. There have been in the repertoire and performances of classical drama.

In 1950, the artistic director of the Grodno Drama Theater became director Yu Yurlovsky. Since his arrival in the repertory there are performances of the works of Belarusian national subjects, as well as productions of plays by contemporary playwrights.

In 1960-1970-ies repertoire mainly consisted of pieces of revolution history.

Since the 1980s, in the Drama Theater raised acute social problems, as well as address the issue of morality and ethics in modern society.

Currently the theater's repertoire is much improved. The team reached the advanced creative directors and actors. Among the latest productions of the theater such masterpieces of world drama as "Tricks of Love" by Lope de Vega, "One Flew Over the Cuckoo's Nest" D. Wasserman, "Taras on Parnassus" S. Kovalev, "Raskidanae gnyazdo" Kupala.

The theater's repertoire, not only adult performances. Specially designed for young viewers Children's repertoire in which such wonderful performances, like "Birthday of Leopold", "Aibolit and Barmaley," "The Tale of the wild forest."

In 1980, architect G. Machulsky was erected a large modern theater building in brick and reinforced concrete, like a crown. Login decorated sculpture L. Zilber. The new building two modern comfortable auditoria: the amphitheater and a large balcony seats 700 seats and a small hall for 216 seats on the ground floor.

Recently, the theater celebrated its 65th anniversary. This momentous event was marked with a grand theatrical presentation honoring the creative theater group.