Natural Science Museum is the largest museum in the city of Plovdiv and the second largest in Bulgaria. The idea of ​​creating the complex was approved by the city authorities in 1952. However, it took several years to gather a rich collection and arrange exhibition space.

September 5, 1955 was the opening of a temporary exhibition of materials of the future natural science museum, which was a great success - it was visited by tens of thousands of residents and guests of Plovdiv.

The first complete exposition opened May 8, 1960. It was dedicated to the geology, flora and fauna of Bulgaria and consisted of several sections: "The evolution of organisms and inanimate nature", "plants", "Invertebrates", "vertebrates - fish, amphibians, reptiles, birds and mammals." This exhibition marked the beginning of the future development of the museum. In 1970-1971 gg. was extension of the museum fund, which is replenished departments of geology, botany, zoology, invertebrates and vertebrates.

In 1974, as a result of the huge research work the museum staff have been renovated and artistically decorated rooms, which are exhibitions of "Geology", "Botany", etc., There are new sections: "Minerals Rhodope Massif" and "Edible and poisonous mushrooms "" Protected natural objects and plants Plovdiv region "and so on. d. In the same year a large-scale exhibition of works" Freshwater ". In the room of 100 square meters. located 44 meters from the aquarium 32 kinds of ornamental fish and exotic plants.

In 1985, the opening of new halls, "Fish" and "seabed". In the latter you can see such unique exotic representatives of the underwater world, like snails, clams, coral and starfish collected off the coast of Angola.

The museum's library, located in a separate building. It collected a large number of different publications in Russian natural-science nature, Bulgarian, English, German and other languages. Today in the library collection has about 8000 volumes.

Since 2006, the complex is called the Regional natural science museum. Exhibitions of the museum complex, which presents a huge number of samples of animate and inanimate nature, will be equally interesting to both adults and young visitors.