Saint Spyridon Church, located in the center of Corfu (Kerkyra) is the largest Orthodox church on the island. Initially, the church of St. Spyridon was in the area Sarokko, but in 1590 the church was built on its present site. Venetian architecture of the temple is typical for the whole of the Old Town and its bell tower is the tallest building in the city and it can be seen even from the ferry when you get close to the coastline (the bell tower as seen from any point of the city). The interior of the church impresses with its grandeur and wealth.

Saint Spyridon was born in 270 AD in the village of Assia Cyprus. In his youth he was a poor and humble shepherd. Later he married and had a daughter. After his wife's death he led a monastic life. St. Spyridon participated in the First Ecumenical Council in Nicaea in 325, which denounced the Arian heresy, revealing a clear proof of the unity of God in the Holy Trinity. He performed many miracles and became revered during his lifetime. Saint Spyridon served as bishop of the city Trimifunta Cyprus (Larnaca District) until his death in 348 year. The relics of the saint remained in Cyprus for 300 years after his death, and at the end of the 7th century were transferred to Constantinople. In 1453, after the capture of Constantinople by the Turks, the relics of Saint Spyridon were taken to Corfu where they are stored today.

The locals are very honored St. Spyridon and consider it the guardian of Corfu. According to legend, he saved four times the island from the danger: in 1533 from hunger in 1629 and 1673 respectively by the plague and in 1716 against the invasion of the Ottoman invaders. The name "Spiridon" is very common on the island. Five times a year, the power carried out of the temple and performed the solemn procession of memory of St Spyridon (December 12 - Day of Remembrance of the saint, on Palm Sunday, Good Friday, on the first Sunday of November and August 12).

Saint Spyridon and revered throughout the world. Every year thousands of pilgrims come to Corfu from all corners of the earth, to worship his holy relics.