Church of Panagia Ahiropitos in Thessaloniki - one of the oldest early Christian churches that have survived to the present day. It is located in the heart of the capital of Greek Macedonia, on the street Agias Sofias, across from Square Makedonomahon.

The church was built around the middle of the 5th century on the ruins of an ancient Roman structures (fragments of a Roman floor mosaic survived to this day), and was known as the Church of Our Lady. During its long history of temple architecture and its interior, of course, has undergone some changes, however, retaining a significant portion of the original structure. In 1430, after the capture of Thessaloniki by the Ottoman Empire, it was the church of Panagia Ahiropitos the first Christian churches were converted into a mosque Eski Camii, as evidenced by the inscription preserved on one of the columns. The temple was the main mosque in the city throughout the rule of the Turks in Salonika.

Church of Panagia Ahiropitos is a three-nave basilica with a wooden roof. Aisles are separated by marble columns, capitals are decorated with two rows of elegant leaves, which is characteristic of Corinthian. The interior of the temple have survived fragments of mosaics dating from the 5th century and beautiful frescoes of the 13th century depicting the Forty Martyrs of Sebaste.

The modern name of the church was first mentioned in documents in 1320, and probably comes from the miraculous icon of the Virgin Mary, which was kept in the temple and was considered miraculous ("Ahiropitos" in Greek means "miraculous, divine origin").

Today, the church of Panagia Ahiropitos is one of the main attractions of Thessaloniki, as well as an important historical and architectural monument. In 1988, the Church of Panagia Ahiropitos along with other early Christian and Byzantine monuments of Thessaloniki became a UNESCO World Heritage Site.