Museum of Science and Industry, located in Manchester, tells the story of the development of science, industry and technology, with emphasis on the role of Manchester.

Manchester has always been famous for the fact that it carried out the most advanced scientific research, carried out the most daring and innovative engineering and technology projects. A well-known proverb: "Tomorrow the whole world will do what Manchester does today." It was here that was started the first passenger railroad, made the first computer that stores the program in its memory. Here John Dalton studied the problems of human perception of colors and described the visual disorder that is now called "color blindness". It was dug first making a profit channel. Here they were made important discoveries in the field of nuclear physics.

The museum was opened in 1969 as Northwest Museum of Science and Industry. In 1978, Manchester City Council bought from British Rail Station Liverpool old building for a nominal sum of one pound sterling. In 1983 the museum moved to the building of the station.

The museum consists of several sections devoted to the history and development of aviation, railways, computing, communications, and so forth.