Botanical Garden of the Rostov University proposed the establishment at the beginning of the XX century on the initiative of the scientific intelligentsia in connection with the evacuation of the Warsaw University in Rostov-on-Don in 1915 .  However, it has become possible with the active participation of professors in the University of Rostov . H . Vershkovskogo and B . F . Khmelevskiy only 1927, when the city authorities have allocated land in the north-western part of Rostov .  This territory was located before the revolution successful flower farm Ramm brothers, natives of Holland .  Closer to the river bed Temernik located land for cultivation of summer crops, and further from the river - greenhouses for winter forcing flowering plants to the Christmas and Easter .  The brothers were engaged in the cultivation of large number of seedlings of ornamental and fruit plants, the selection work carried out by hybridization of roses on the basis of the best varieties imported from France and Germany .  Produced fairly large catalog of ornamental, fruit plants and seeds, only hybrid tea roses Brother offers about 400 varieties . 

At the end of 1928 the botanical garden was transferred to the North Caucasus (Rostov, and today - Southern Federal) University. In a short time the park was laid forest type and an arboretum of more than 400 new species to the region. During World War II most of the plants and buildings were lost. Now of prewar planting and kept in good condition 54 species, including beech, hornbeam, Celtis australis and Mississippi, Amur velvet, Chekalkin walnut, oak macrocarpa and krupnopylnikovy, small-leaved elm. Most older plants - pedunculate oak - more than 120 years.

Currently, the Botanical Garden is an educational and scientific division of the Southern Federal University, occupies 160 hectares classified as natural monuments of regional significance.