Muslim mosque Kara Mousa Pasha is located at the intersection of Arcade (one of the main shopping streets) and Victor Hugo's far from Heroes' Square. Like most of the Ottoman buildings on the island, this building was the first of the Venetian structure.

During the Venetian rule the building housed the cathedral of St. Barbara. Impressive Renaissance facades with ornate doorways and balconies are at this time.

The mosque was named after the famous Ottoman admiral and statesman Kara Musa Pasha, commander of the Navy, in 1646 to conquer the city of Rethymnon. After the establishment of Turkish rule, the city's architecture has changed, enriched by an impressive Muslim flavor.

Redid the Cathedral of St. Barbara in the mosque, the Turks added a dome and minaret. Near the entrance to the mosque there is a fountain in which believers could bathe before visiting the monastery. Dilapidated minaret is located in the western part of the building. In the courtyard is a vaulted tomb, which probably was buried the founder of the mosque. Also in the courtyard are preserved numerous Muslim tombstones.

A remarkable architectural monument as a whole is very well preserved to the present day. Today a Muslim mosque Kara Mousa Pasha closed to visitors. The building is located Inspectorate of Byzantine Antiquities, and carried out restoration work. Admire the beautiful ancient structure, which mixed a great Venetian and Turkish architecture, it is possible is through the outer gates locked.