Science Museum in Osaka is known for its planetarium, which is the fifth largest in the world. In 1935, the Osaka municipality announced the purchase of the projector manufactured by Carl Zeiss. It was about the device, which transmit images of celestial bodies on the screen. The museum was opened in 1937 and located in the planetarium it enjoyed great popularity, including his visits manga author, the creator of "Astro-Boy," Osamu Tezuka and science fiction writer Sakё Komatsu.

At the end of the 80s of the last century the Municipal Museum of Electrical Engineering was disbanded and in its place was created by the Museum of Science. Its opening was timed to celebrate the 100th anniversary of Osaka in 1989. On the construction of a new building for the museum has been allocated more than six million dollars. Re-opening of the renovated planetarium was held only in 2004.

The Science Museum Osaka four floors, each of which is devoted to specific topics .  In total, the museum has more than two hundred pieces, many of them can touch, examine and conduct experiments .  On the first floor objects and devices that demonstrate the physical properties of light, sound and air .  On the second floor all comers offer to conduct a variety of experiments with computing devices and sensors, as well as to see optical illusions .  The third floor is dedicated to the theme of electricity .  Here are the different types of power generators, their work can be seen in action - for example, is transformed into electricity kinetic energy of water .  The fourth floor is for exhibits dedicated to the universe .  In this part of the museum can observe celestial bodies with a telescope, hold in their hands a fragment of the meteorite, and see a small copy of the planets of the solar system and the Sun, as well as the globe diameter of 2 meters .

The museum regularly hosts presentation on scientific topics.